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Madison Smith's Website - Viewing Journal - Friday, December 26, 2003 7:00 PM
Thank you for taking time to inquire about Madison and how she is doing. Madison was diagnosed with high risk T-cell Acute Lymphocytic Leukemia on September 24, 2003 at Duke Hospital in North Carolina. She had just turned three at that time. Leukemia is a blood cancer that is not believed by medical professionals to be inherited at this time. She presented with a mass in her chest that encompassed the majority of the upper half of her chest area. The mass was related to the leukemia. It collapsed her left lung and a portion of her right lung and was shutting off the blood flow from her heart to the rest of her body. She was in the pediatric intensive care unit for almost two weeks on a ventilator. We weren't sure then if we would ever have a chance to fight the leukemia. Madi is a true fighter and pulled through! After getting off the vent, Madison was able to achieve remission by the 28th day of treatment. She underwent two and half years of aggressive chemotherapy (protocol 1961) and radiation for the mass. On Christmas Eve 2005, a little over two years after her diagnosis Madison had a chest CT done that revealed that the mass was finally gone! Madison finished her treatment in January 2006. Children that have cancer are not considered "cured" until they have been off treatment with no-reoccurrence for five years. Duke has followed Madison throughout her treatment. She will continue to be followed by Duke. In April 2008 Duke uncovered that Madison has an obstruction in 3 of her veins. The veins involved are the Left innominate vein, the left (lower) internal jugular vein, and her sub-clavian vein. These veins are responsible for carrying her blood back to her heart and hers are 100% occluded. What is going on with her right now is likely a result of the mass she had in 2003. There aren't really any easy fixes for what is going on with her and no real cases that it can be compared to. We are working with Duke in an effort to resolve this issue. In February 2011, Madi moved from in-remission to "CURED" from her disease We've come this far for a reason! Please continue to lift all of us up. The care and concern that we have felt from all of you continues to be an encouragement to us. Thank you...
 
- Allison

Update - Friday, December 26, 2003 7:00 PM


Madison is still admitted at Barnes-Jewish Children's Hospital in St. Louis, Mo. Since being admitted her counts have not made a change for the better or worse. This means that they are still way too low for her to be able to leave the hospital. Her doctor gave her a medicine today that is supposed to help boost her white blood cells and in turn should help her counts rebound. She has not had this medicine before. It is supposed to take anywhere from 48-72 hours to work. Madison has felt good today and has been a real chatter-box.

We have seen Madi's counts make drastic changes within one day. We are hoping that perhaps tomorrow they will have risen a little bit on their own. In order for Madi to be released her doctors will have to see an upward trend in her counts rising back towards the magic number of 500. They are currently 16. Until then, we will hope for the best!!

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